Improve product convenience and acceptability through lower dosage frequency and enhanced safety

ORBEXA™, a solvent-based granulation and extrusion technology is applicable for capsules and single unit sachets. The granulation spheronization and extrusion techniques produce beads of controlled size and density. The beads are coated with functional polymers to provide high drug concentrations and additional rates of control. The technology’s high-speed process can accommodate sensitive molecules like proteins and are suitable for high drug loading.

How it works
Granulation spheronization and extrusion techniques produce beads of controlled size and density. These beads can be coated with functional polymers to provide high drug concentrations and additional rates of control.

Key advantages

  • High-level of controlled release
  • Aqueous or solvent-based granulation
  • High-speed process can accommodate sensitive molecules like proteins
  • Suitable for high drug loading
  • Appropriate for capsules or single-dose sachets

Speak With An Expert

Profile Photo: Luigi Boltri

Luigi Boltri

Director, Technology Development

Dr. Boltri is a pharmaceutical chemist by training and completed his degree at the University of Turin. With almost 30 years of experience in the Pharmaceutical Industry, Dr Boltri has held leading positions as Department Head and Director.

 

He has extensive formulation development experience in various dosage forms, with a focus on oral delivery and bioavailability enhancement.

 

Dr. Boltri has overseen the development of 15 original/innovative products from prototype profiling to commercial scale.

 

In his current role, Dr. Boltri supports company processes leading to identify new and innovative technologies, as well as valuable opportunities for product development and co-development.

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